Macrophage Activation Syndrome in a Child with Systemic Juvenile Rheumatoid Arthritis

Macrophage Activation Syndrome in a Child with Systemic Juvenile Rheumatoid Arthritis

Macrophage activation syndrome (MAS) is a rare and potentially fatal complication of rheumatic disorders in children. We describe a 13-month-old boy in whom MAS developed as a complication of systemic juvenile rheumatoid arthritis (S-JRA). He suffered from fever and generalized rash followed by multiple joints swelling for four months before admission. Physical examination revealed cervical lym...

A case of macrophage activation syndrome in a child with systemic juvenile idiopathic arthritis

Results History of the disease: the beginning of the disease was characterized with erythematosis rash and febrile temperature. Infectious diseases were excluded. Therapy with 10 mg of prednisolone per day had a temporary positive effect. However, varicella relapse with recurrent fever took place 3 weeks after. The following symptoms have been reported: fever up to 39.0C, a rash on the upper li...

Macrophage Activation Syndrome and Etanercept in Children with Systemic Juvenile Rheumatoid Arthritis

Macrophage activation syndrome as a complication of juvenile rheumatoid arthritis.

OBJECTIVE Juvenile rheumatoid arthritis (JRA), also known as juvenile idiopathic arthritis (JIA), is a rare autoimmune joint disorder of children. The concrete causes for the prevalence of the above pathological state are still unknown. In other words, it is an arthritis affecting mainly children and adolescents. Clinically, it has 3 different clinical subtypes. JRA patients are often noticed w...

Macrophage activation syndrome and etanercept in children with systemic juvenile rheumatoid arthritis.